Heads at the Chisana Glacier and flows NE 60 mi and then NW 45 mi to join the Nabesna River to form the Tanana River.
Indian name sometimes written "Ches-tna" meaning "red river;" reported in 1885 by Lieutenant Allen (1887, Map of Explorations); USA.
Andrew Lake, Birch Lake, Cemetery Lake, Chidek Lake, Clearwater Lake, Damundtali Lake, Dog Lake, Eliza Lake, Fish Lake, Hillside Lake, Hudeuc Lake, Long Lake, Pauline Lakes, Pullin Lake, Shashamund Lake, Skate Lake, Steve Lake, Thadthamund Lake, Tontethaimund Lake, Tsolmund Lake, Tushaday Lake, Yarger Lake,
Mountains:Rivers:Streams:Streams:Beaver Creek, Charlieskin Creek, Chindaglekne Creek, Mark Creek, Moose Creek, Open Creek, Silver Creek, Stuver Creek,
Cities:Charlieskin Village, Kathakne, Nabesna Village, Northway Junction, Northway Village,